EDC4 Antikörper (AA 1-100)
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- Target Alle EDC4 Antikörper anzeigen
- EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
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Bindungsspezifität
- AA 1-100
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EDC4 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Sheep,Pig,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EDC4
- Isotyp
- IgG
- Top Product
- Discover our top product EDC4 Primärantikörper
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- Applikationshinweise
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
- Andere Bezeichnung
- EDC4 (EDC4 Produkte)
- Synonyme
- VARICOSE antikoerper, ge-1 antikoerper, hedls antikoerper, rcd-8 antikoerper, GE1 antikoerper, Ge-1 antikoerper, HEDL5 antikoerper, HEDLS antikoerper, RCD-8 antikoerper, RCD8 antikoerper, BC022641 antikoerper, si:ch211-237c7.1 antikoerper, wu:fe26b05 antikoerper, LRRG00115 antikoerper, Nrn1l antikoerper, RGD1309136 antikoerper, enhancer of mRNA decapping 4 antikoerper, Transducin/WD40 repeat-like superfamily protein antikoerper, enhancer of mRNA decapping 4 L homeolog antikoerper, EDC4 antikoerper, VCS antikoerper, edc4 antikoerper, Edc4 antikoerper, edc4.L antikoerper
- Hintergrund
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Synonyms: autoantigen, Autoantigen Ge 1, Autoantigen Ge-1, Autoantigen Ge1, Autoantigen RCD 8, Autoantigen RCD-8, Autoantigen RCD8, edc4, EDC4_HUMAN, Enhancer of mRNA decapping 4, Enhancer of mRNA-decapping protein 4, Ge 1, Hedls, Human enhancer of decapping large subunit, RCD 8.
Background: The major eukaryotic mRNA decay pathway occurs through deadenylation, decapping, and 5' to 3' degradation of the mRNA. Decapping is a critical control point in this decay pathway. Edc4 (enhancer of mRNA decapping 4), also known as human enhancer of decapping large subunit (HEDLS), RCD-8 or Ge-1, is a 1,401 amino acid protein belonging to the WD repeat EDC4 family that is involved in mRNA decapping during mRNA degradation. As part of the mRNA degradation process, Edc4 becomes part of a complex that also contains hDcp1a, hDcp2a, RCK and Edc3. Localizing to P-body and cytoplasm, Edc4 contains a nuclear localization sequence (NLS) which enables it to selectively enter the nucleus as well. Edc4 becomes phosphorylated upon DNA damage and exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 16q22.1.
- Gen-ID
- 23644
- UniProt
- Q6P2E9
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