Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

EDC4 Antikörper (AA 1-100)

EDC4 Reaktivität: Human, Maus, Ratte ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6989158
  • Target Alle EDC4 Antikörper anzeigen
    EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
    Bindungsspezifität
    • 14
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 40
    • 29
    • 26
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 37
    • 3
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EDC4 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 12
    • 11
    • 10
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EDC4
    Isotyp
    IgG
    Top Product
    Discover our top product EDC4 Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
    Andere Bezeichnung
    EDC4 (EDC4 Produkte)
    Synonyme
    VARICOSE antikoerper, ge-1 antikoerper, hedls antikoerper, rcd-8 antikoerper, GE1 antikoerper, Ge-1 antikoerper, HEDL5 antikoerper, HEDLS antikoerper, RCD-8 antikoerper, RCD8 antikoerper, BC022641 antikoerper, si:ch211-237c7.1 antikoerper, wu:fe26b05 antikoerper, LRRG00115 antikoerper, Nrn1l antikoerper, RGD1309136 antikoerper, enhancer of mRNA decapping 4 antikoerper, Transducin/WD40 repeat-like superfamily protein antikoerper, enhancer of mRNA decapping 4 L homeolog antikoerper, EDC4 antikoerper, VCS antikoerper, edc4 antikoerper, Edc4 antikoerper, edc4.L antikoerper
    Hintergrund

    Synonyms: autoantigen, Autoantigen Ge 1, Autoantigen Ge-1, Autoantigen Ge1, Autoantigen RCD 8, Autoantigen RCD-8, Autoantigen RCD8, edc4, EDC4_HUMAN, Enhancer of mRNA decapping 4, Enhancer of mRNA-decapping protein 4, Ge 1, Hedls, Human enhancer of decapping large subunit, RCD 8.

    Background: The major eukaryotic mRNA decay pathway occurs through deadenylation, decapping, and 5' to 3' degradation of the mRNA. Decapping is a critical control point in this decay pathway. Edc4 (enhancer of mRNA decapping 4), also known as human enhancer of decapping large subunit (HEDLS), RCD-8 or Ge-1, is a 1,401 amino acid protein belonging to the WD repeat EDC4 family that is involved in mRNA decapping during mRNA degradation. As part of the mRNA degradation process, Edc4 becomes part of a complex that also contains hDcp1a, hDcp2a, RCK and Edc3. Localizing to P-body and cytoplasm, Edc4 contains a nuclear localization sequence (NLS) which enables it to selectively enter the nucleus as well. Edc4 becomes phosphorylated upon DNA damage and exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 16q22.1.

    Gen-ID
    23644
    UniProt
    Q6P2E9
Sie sind hier:
Kundenservice