FKBP1B Antikörper (AA 21-100)

Produktnummer ABIN6989185

Produktdetails anti-FKBP1B Antikörper

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Bindungsspezifität: AA 21-100

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP1B Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FKBP1B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FKBP1B

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Andere Bezeichnung: FKBP1B (FKBP1B Produkte)

Synonyme: FKBP12.6 antikoerper, MGC68829 antikoerper, FKBP1B antikoerper, DKFZp459K1429 antikoerper, 12.6kDa antikoerper, AW494148 antikoerper, calstabin2 antikoerper, FKBP1L antikoerper, OTK4 antikoerper, PKBP1L antikoerper, PPIase antikoerper, FK506 binding protein 1B antikoerper, FK506 binding protein 1B L homeolog antikoerper, FK506 binding protein 1b antikoerper, FKBP1B antikoerper, fkbp1b.L antikoerper, fkbp1b antikoerper, Fkbp1b antikoerper

Hintergrund:

Synonyms: 12.6 kDa FK506-binding protein, 12.6 kDa FKBP, Calstabin 2, FK506 binding protein 1 like, FK506 binding protein 12.6, FK506 binding protein 1B 12.6 kDa, FK506 binding protein 1B, FK506-binding protein 1B, FKB1B_HUMAN, FKBP 12.6, FKBP 1B, FKBP 1L, FKBP 9, FKBP-12.6, FKBP-1B, FKBP12.6, Fkbp1b, FKBP1L, FKBP9, h FKBP 12, h-FKBP-12, Immunophilin FKBP12.6, OTK 4, OTK4, Peptidyl prolyl cis trans isomerase 1B, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP1B, PKBP 1L, PKBP1L, PPIase 1B, PPIase, PPIase FKBP1B, Rotamase 1B, Rotamase

Background: Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Gen-ID: 2281

UniProt: P68106

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity