SYNCRIP Antikörper (AA 51-150)

Produktnummer ABIN6989206

Produktdetails anti-SYNCRIP Antikörper

Target: SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))

Bindungsspezifität: AA 51-150

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNCRIP Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human hnRNP Q

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SYNCRIP

Target: SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))

Andere Bezeichnung: hnRNP Q (SYNCRIP Produkte)

Synonyme: GRY-RBP antikoerper, GRYRBP antikoerper, HNRNPQ antikoerper, HNRPQ1 antikoerper, NSAP1 antikoerper, PP68 antikoerper, hnRNP-Q antikoerper, 2610109K23Rik antikoerper, 4632417O19Rik antikoerper, Nsap1 antikoerper, Nsap1l antikoerper, pp68 antikoerper, nsap1 antikoerper, wu:fe02c03 antikoerper, wu:fe47h09 antikoerper, SYNCRIP antikoerper, hnrpq1 antikoerper, gry-rbp antikoerper, rp1-3j17.2 antikoerper, synaptotagmin binding cytoplasmic RNA interacting protein antikoerper, synaptotagmin binding, cytoplasmic RNA interacting protein antikoerper, synaptotagmin binding cytoplasmic RNA interacting protein S homeolog antikoerper, SYNCRIP antikoerper, Syncrip antikoerper, syncrip antikoerper, syncrip.S antikoerper

Hintergrund:

Synonyms: cytoplasmic RNA-interacting protein, dJ3J17.2, Glycine and tyrosine rich RNA binding protein, Glycine- and tyrosine-rich RNA-binding protein, GRY RBP, GRY-RBP, Heterogeneous nuclear ribonucleoprotein Q, hnRNP Q, HNRPQ 1, HNRPQ, HNRPQ_HUMAN, HNRPQ1, NS1 associated protein 1, NS1-associated protein 1, NSAP 1, NSAP1, pp68, RP1 3J17.2, Synaptotagmin binding cytoplasmic RNA interacting protein, Synaptotagmin-binding, SYNCRIP.

Background: Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.

Gen-ID: 10492

UniProt: O60506