NEK6 Antikörper (AA 81-180)

Produktnummer ABIN6989319

Produktdetails anti-NEK6 Antikörper

Target: NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))

Bindungsspezifität: AA 81-180

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEK6 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NEK6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NEK6

Target: NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))

Andere Bezeichnung: NEK6 (NEK6 Produkte)

Synonyme: 1300007C09Rik antikoerper, si:ch211-167p9.4 antikoerper, ATNEK5 antikoerper, MOE17.17 antikoerper, NIMA-RELATED KINASE5 antikoerper, NIMA-related kinase 5 antikoerper, SID6-1512 antikoerper, NIMA (never in mitosis gene a)-related expressed kinase 6 antikoerper, NIMA-related kinase 6 antikoerper, NIMA related kinase 6 antikoerper, Serine/Threonine kinase catalytic domain protein antikoerper, NIMA-related kinase 6 S homeolog antikoerper, Nek6 antikoerper, nek6 antikoerper, NEK6 antikoerper, NEK5 antikoerper, nek6.S antikoerper

Hintergrund:

Synonyms: Highly similar to cell cycle protein kinase CDC5/MSD2, NEK6, NEK6_HUMAN, Never in mitosis A-related kinase 6, NIMA (Never In Mitosis Gene A) Related Kinase 6, NimA related protein kinase 6, NimA-related protein kinase 6, Protein kinase SID6 1512, Protein kinase SID6-1512, Putative serine threonine protein kinase, Serine/threonine protein kinase Nek6, Serine/threonine-protein kinase Nek6, SID61512.

Background: Protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates KIF11 to promote mitotic spindle formation. Involved in G2/M phase cell cycle arrest induced by DNA damage. Inhibition of activity results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence.

Gen-ID: 10783

UniProt: Q9HC98