WAPAL Antikörper

Produktnummer ABIN6989652

Produktdetails anti-WAPAL Antikörper

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser WAPAL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: Synthetic Peptide within N-terminal human WAPL

Klon: 7C15

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu WAPAL

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Andere Bezeichnung: WAPL (WAPAL Produkte)

Synonyme: RGD1308960 antikoerper, FOE antikoerper, KIAA0261 antikoerper, WAPL antikoerper, 2410073G16 antikoerper, A530089A20Rik antikoerper, BC037674 antikoerper, mKIAA0261 antikoerper, mWAPL antikoerper, WAPL cohesin release factor antikoerper, Wapl antikoerper, WAPL antikoerper, wapl antikoerper

Hintergrund:

Synonyms: FOE antibody, Friend of EBNA2 (Epstein Barr virus nuclear protein 2) antibody, Friend of EBNA2 protein antibody, KIAA0261 antibody, OTTHUMP00000020004 antibody, WAPAL antibody, WAPL antibody, WAPL_HUMAN antibody, Wings apart like homolog antibody, Wings apart like homolog (Drosophila) antibody, Wings apart-like protein homolog antibody

Background: Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Tissue specificity: Isoform 1 is highly expressed in uterine cervix tumor. Isoform 2 is widely expressed with a high level in skeletal muscle and heart.

Gen-ID: 23063

UniProt: Q7Z5K2

Pathways: Chromatin Binding