HLA-F Antikörper
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- Target Alle HLA-F (HLAF) Antikörper anzeigen
- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser HLA-F Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Synthetic Peptide corresponding to C terminal human HLA F.
- Klon
- 4H
- Isotyp
- IgG
- Top Product
- Discover our top product HLAF Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
- Andere Bezeichnung
- HLA F (HLAF Produkte)
- Synonyme
- HLAF antikoerper, CDA12 antikoerper, HLA-5.4 antikoerper, HLA-CDA12 antikoerper, major histocompatibility complex, class I, F antikoerper, HLA-F antikoerper
- Hintergrund
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Synonyms: CDA12 antibody, HLA 5.4 antibody, HLA class I histocompatibility antigen, alpha chain F antibody, HLA class I molecule antibody, HLA F antigen antibody, HLA-CDA12 antibody, HLA-F antibody, HLAF antibody, HLAF_HUMAN antibody, Leukocyte antigen F antibody, MHC class I antigen F antibody
Background: This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq, Jul 2008]
- Gen-ID
- 3134
- UniProt
- P30511
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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