EGLN1 Antikörper
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- Target Alle EGLN1 Antikörper anzeigen
- EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EGLN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-426 of human EGLN1 (NP_071334.1).
- Isotyp
- IgG
- Top Product
- Discover our top product EGLN1 Primärantikörper
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anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 1-426) antibody
KO Validated EGLN1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 301-426) antibodyEGLN1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 42-140) antibodyEGLN1 Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 272-355) antibodyEGLN1 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (Internal Region) antibodyEGLN1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) antibodyEGLN1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 301-426) antibodyEGLN1 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 396-425), (C-Term) antibodyEGLN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB39542 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 1-24) antibodyEGLN1 Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal 366G-76-3 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (C-Term) antibodyEGLN1 Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Affe, Rind (Kuh), Meerschweinchen, Pferd, Huhn, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()
IF() - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
- Andere Bezeichnung
- EGLN1 (EGLN1 Produkte)
- Hintergrund
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Synonyms: EGLN1,C1orf12,ECYT3,HALAH,HIF-PH2,HIFPH2,HPH-2,HPH2,PHD2,SM20,ZMYND6
Background: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).
- Gen-ID
- 54583
- UniProt
- Q9GZT9
- Pathways
- cAMP Metabolic Process, Warburg Effekt
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