SARS-CoV-2 Spike S1 Antikörper

Produktnummer ABIN6990098

Produktdetails anti-SARS-CoV-2 Spike S1 Antikörper

Target: SARS-CoV-2 Spike S1

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Human

Klonalität: Monoklonal

Konjugat: Dieser SARS-CoV-2 Spike S1 Antikörper ist unkonjugiert

Applikation: ELISA

Spezifität: Antibody recognizes 2019-nCoV S1 Protein/ 2019-nCoV S-RBD Protein.

Reinheit: 95,00%

Immunogen: Cultured in vitro under conditions free from animal derived components.

Klon: 5D9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoreactivity: 80-120 % compared to the reference sample in an ELISA test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.0 mg/mL

Buffer: PBS, pH 7.4

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: 24 months from manufacturing at <-20 °C, 1 month, 2 to 8 °C under sterile conditions.

Details zu SARS-CoV-2 Spike S1

Target: SARS-CoV-2 Spike S1

Andere Bezeichnung: SARS-CoV-2 S1 (SARS-CoV-2 Spike S1 Produkte)

Synonyme: E2 antikoerper, Surface Glycoprotein antikoerper, S antikoerper

Substanzklasse: Viral Protein

Hintergrund: The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Gen-ID: 43740568