Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SARS-CoV-2 Spike S2 Antikörper (C-Term)

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990132
  • Target Alle SARS-CoV-2 Spike S2 Antikörper anzeigen
    SARS-CoV-2 Spike S2
    Bindungsspezifität
    • 1
    • 1
    • 1
    • 1
    AA 1130-1180, C-Term
    Reaktivität
    SARS Coronavirus-2 (SARS-CoV-2)
    Wirt
    • 5
    • 4
    • 2
    Kaninchen
    Klonalität
    • 6
    • 4
    Polyklonal
    Konjugat
    • 8
    • 2
    Dieser SARS-CoV-2 Spike S2 Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Aufreinigung
    SARS-CoV-2 (COVID-19) Spike Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Anti-SARS-CoV-2 (COVID-19) Spike S2 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of SARS-CoV-2 (COVID-19) Spike glycoprotein. The immunogen is located within 1130-1180 amino acids of SARS-CoV-2 (COVID-19) Spike protein.
    Isotyp
    IgG
    Top Product
    Discover our top product SARS-CoV-2 Spike S2 Primärantikörper
  • Applikationshinweise
    WB: 1 μ,g/mL, IHC: 0.1 μ,g/mL, IF: 10 μ,g/mL.

    Antibody validated: Immunohistochemistry and Immunofluorescence in human samples. SARS-CoV-2 (COVID-19) Spike antibody can be used for the detection of SARS-CoV-2 (COVID-19) Spike protein in ELISA. It will detect 4 ng of free peptide at 1 μ,g/mL. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    SARS-CoV-2 (COVID-19) Spike Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    SARS-CoV-2 (COVID-19) Spike antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SARS-CoV-2 Spike S2
    Abstract
    SARS-CoV-2 Spike S2 Produkte
    Synonyme
    E2 antikoerper, Surface Glycoprotein antikoerper, S antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).
    Gen-ID
    43740568
Sie sind hier:
Kundenservice