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SARS-CoV-2 ORF6 Antikörper (C-Term)

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2) ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990152
  • Target Alle SARS-CoV-2 ORF6 Produkte
    SARS-CoV-2 ORF6
    Bindungsspezifität
    C-Term
    Reaktivität
    SARS Coronavirus-2 (SARS-CoV-2)
    Wirt
    • 1
    Kaninchen
    Klonalität
    • 1
    Polyklonal
    Konjugat
    • 1
    Dieser SARS-CoV-2 ORF6 Antikörper ist unkonjugiert
    Applikation
    • 1
    • 1
    ELISA
    Aufreinigung
    SARS-CoV-2 (COVID-19) ORF6 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Anti-SARS-CoV-2 (COVID-19) ORF6 antibody was raised against a peptide corresponding to 15 amino acids near the Carboxyl terminus of SARS-CoV-2 (COVID-19) ORF6 protein. The immunogen is located in the last 50 amino acids of SARS-CoV-2 (COVID-19) ORF6.
    Isotyp
    IgG
  • Applikationshinweise
    Antibody validated: SARS-CoV-2 (COVID-19) ORF6 antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    SARS-CoV-2 (COVID-19) ORF6 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    SARS-CoV-2 (COVID-19) ORF6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SARS-CoV-2 ORF6
    Abstract
    SARS-CoV-2 ORF6 Produkte
    Synonyme
    ORF6 protein antikoerper, ORF6 antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. ORF6 disrupts cell nuclear import complex formation by tethering karyopherin alpha 2 and karyopherin beta 1 to the membrane. Retention of import factors at the ER/Golgi membrane leads to a loss of transport into the nucleus. Thereby it prevents STAT1 nuclear translocation in response to interferon signaling, thus blocking the expression of interferon stimulated genes (ISGs) that display multiple antiviral activities(3).
    Gen-ID
    43740572
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