GFRA3 Antikörper

Produktnummer ABIN6990252

Produktdetails anti-GFRA3 Antikörper

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFRA3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: GFR alpha 3 Antibody is Antibody is DEAE purified.

Immunogen: GFR alpha 3 antibody was raised against a 14 amino acid peptide near the center of murine GFR alpha 3. The immunogen is located within the last 50 amino acids of GFR alpha 3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GFR alpha 3 antibody can be used for detection of GFR alpha 3 expression by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GFR alpha 3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: GFR alpha 3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GFRA3

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Andere Bezeichnung: GFR alpha 3 (GFRA3 Produkte)

Synonyme: GFRA3 antikoerper, GFRalpha3 antikoerper, Y15110 antikoerper, GDNF family receptor alpha 3 antikoerper, glial cell line derived neurotrophic factor family receptor alpha 3 antikoerper, Gfra3 antikoerper, GFRA3 antikoerper

Hintergrund: GFR alpha 3 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRα, and Ret receptor tyrosine kinase GFRbeta. Following the findings of GFRα,-1 and -2, a novel receptor in GFRα, family was identified from human and mouse and designated GFRα,-3. GFRα,-3 binds persephin, thus, persephin, GFRα,-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.

Molekulargewicht: Predicted: 44 kDa

Observed: 43 kDa

Gen-ID: 14587

NCBI Accession: NP_034410

UniProt: O35118