ACIN1 Antikörper (C-Term)

Produktnummer ABIN6990315

Produktdetails anti-ACIN1 Antikörper

Target: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Bindungsspezifität: AA 1050-1100, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Aufreinigung: Acinus Antibody is affinity chromatography purified via peptide column.

Immunogen: Acinus antibody was raised against a peptide corresponding to amino acids near the C-terminus of the cleaved active peptide p17, which are identical to those of mouse Acinus. The immunogen is located within amino acids 1050 - 1100 of Acinus.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Acinus antibody can be used for detection of Acinus by Western blot at 1 μ,g/mL. An approximate 220 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Acinus Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Acinus antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ACIN1

Target: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Andere Bezeichnung: Acinus (ACIN1 Produkte)

Synonyme: acinus antikoerper, acinusb antikoerper, fi14c05 antikoerper, wu:fe06a10 antikoerper, wu:fi14c05 antikoerper, acinusa antikoerper, acinusl antikoerper, ik:tdsubc_2g5 antikoerper, si:zc14a17.12 antikoerper, wu:fb04g06 antikoerper, wu:fb40f03 antikoerper, wu:fb68h03 antikoerper, wu:fb80f07 antikoerper, wu:fc12e10 antikoerper, xx:tdsubc_2g5 antikoerper, acn antikoerper, ACINUS antikoerper, ACN antikoerper, fSAP152 antikoerper, 2610036I19Rik antikoerper, 2610510L13Rik antikoerper, Acinus antikoerper, Acn antikoerper, C79325 antikoerper, acinusL antikoerper, acinusS antikoerper, mKIAA0670 antikoerper, apoptotic chromatin condensation inducer 1b antikoerper, apoptotic chromatin condensation inducer 1a antikoerper, apoptotic chromatin condensation inducer 1 antikoerper, apoptotic chromatin condensation inducer 1 S homeolog antikoerper, acin1b antikoerper, acin1a antikoerper, acin1 antikoerper, ACIN1 antikoerper, acin1.S antikoerper, Acin1 antikoerper

Hintergrund: Acinus Antibody: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'.

Molekulargewicht: 220 kDa

Gen-ID: 22985

UniProt: Q9UKV3