SKI Antikörper (N-Term)
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- Target Alle SKI Antikörper anzeigen
- SKI (SKI Proto-Oncogene (SKI))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SKI Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Aufreinigung
- Ski Antibody is affinity chromatography purified via peptide column.
- Immunogen
- Ski antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Ski. The immunogen is located within the first 50 amino acids of Ski.
- Isotyp
- IgG
- Top Product
- Discover our top product SKI Primärantikörper
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- Applikationshinweise
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SkiP antibody can be used for detection of Ski by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Ski Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- Ski antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- SKI (SKI Proto-Oncogene (SKI))
- Andere Bezeichnung
- Ski (SKI Produkte)
- Synonyme
- SGS antikoerper, SKV antikoerper, SKI antikoerper, C-SKI antikoerper, RGD1565591 antikoerper, c-ski antikoerper, 2310012I02Rik antikoerper, 2610001A11Rik antikoerper, AA062172 antikoerper, AA589460 antikoerper, BC004088 antikoerper, ski antikoerper, skv antikoerper, xski antikoerper, id:ibd1250 antikoerper, SKI proto-oncogene antikoerper, ski sarcoma viral oncogene homolog (avian) antikoerper, SKI proto-oncogene L homeolog antikoerper, v-ski avian sarcoma viral oncogene homolog a antikoerper, SKI antikoerper, Ski antikoerper, ski.L antikoerper, skia antikoerper
- Hintergrund
- Ski Antibody: TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Ski functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes. Ski will also bind to the Smad proteins specific to bone morphogenic proteins (BMPs) and block BMP signaling in mammalian cells.
- Gen-ID
- 6497
- UniProt
- P12755
- Pathways
- Stem Cell Maintenance, Tube Formation, Skeletal Muscle Fiber Development
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