Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

FLASH Antikörper (C-Term)

CASP8AP2 Reaktivität: Human WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990336
  • Target Alle FLASH (CASP8AP2) Antikörper anzeigen
    FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 17
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 20
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FLASH Antikörper ist unkonjugiert
    Applikation
    • 13
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Aufreinigung
    FLASH Antibody is affinity chromatography purified via peptide column.
    Immunogen
    FLASH antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human FLASH which differ from those of mouse by one amino acid. The immunogen is located within the last 50 amino acids of FLASH.
    Isotyp
    IgG
    Top Product
    Discover our top product CASP8AP2 Primärantikörper
  • Applikationshinweise
    FLASH antibody can be used for detection of FLASH by Western blot at 0.5 μ,g/mL. An approximate 220 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    FLASH Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    FLASH antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
    Andere Bezeichnung
    FLASH (CASP8AP2 Produkte)
    Synonyme
    CASP8AP2 antikoerper, FLASH antikoerper, fc74h10 antikoerper, wu:fc74h10 antikoerper, zgc:113449 antikoerper, CED-4 antikoerper, RIP25 antikoerper, AA387232 antikoerper, D4Ertd659e antikoerper, mKIAA1315 antikoerper, caspase 8 associated protein 2 antikoerper, CASP8AP2 antikoerper, casp8ap2 antikoerper, Casp8ap2 antikoerper
    Hintergrund
    FLASH Antibody: A novel mammalian CED-4 homologous was recently identified and cloned in mouse and human and designated FLASH (for FLICE-associated huge protein). FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8. There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity. FLASH is widely expressed.
    Molekulargewicht
    220 kDa
    Gen-ID
    9994
    UniProt
    Q9UKL3
    Pathways
    Chromatin Binding, Positive Regulation of Endopeptidase Activity
Sie sind hier:
Kundenservice