LRRC1 Antikörper (C-Term)

Produktnummer ABIN6990392

Produktdetails anti-LRRC1 Antikörper

Target: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: Lano Antibody is affinity chromatography purified via peptide column.

Immunogen: Lano antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human Lano. The immunogen is located within the last 50 amino acids of Lano.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Lano antibody can be used for detection of Lano by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Lano Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Lano antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LRRC1

Target: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Andere Bezeichnung: Lano (LRRC1 Produkte)

Synonyme: LRRC1 antikoerper, LANO antikoerper, dJ523E19.1 antikoerper, A430093J20Rik antikoerper, AU016091 antikoerper, D030059I21 antikoerper, mKIAA4018 antikoerper, leucine rich repeat containing 1 antikoerper, Lrrc1 antikoerper, LRRC1 antikoerper

Hintergrund: Lano Antibody: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.

Molekulargewicht: Predicted: 59 kDa

Observed: 59 kDa

Gen-ID: 55227

UniProt: Q9BTT6