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MAP1 Antikörper

MAP1 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990393
  • Target Alle MAP1 Antikörper anzeigen
    MAP1 (Mannosidase Processing 1 (MAP1))
    Reaktivität
    Human, Maus
    Wirt
    • 6
    • 5
    Kaninchen
    Klonalität
    • 6
    • 5
    Polyklonal
    Konjugat
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser MAP1 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    MAP1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    MAP-1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human MAP-1. The immunogen is located within the last 50 amino acids of MAP1.
    Isotyp
    IgG
    Top Product
    Discover our top product MAP1 Primärantikörper
  • Applikationshinweise
    MAP1 antibody can be used for the detection of MAP-1 by Western blot at 1 to 4 μ,g/mL.

    Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    MAP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    MAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    MAP1 (Mannosidase Processing 1 (MAP1))
    Andere Bezeichnung
    MAP1 (MAP1 Produkte)
    Synonyme
    Map-1 antikoerper, Map1 antikoerper, mannosidase processing 1 antikoerper, Blood pressure QTL 196 antikoerper, Map1 antikoerper, Bp196 antikoerper
    Hintergrund
    MAP1 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A related protein termed MAP-1 has recently been identified. This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed. It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo. It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis.
    Gen-ID
    64112
    NCBI Accession
    NP_071434
    UniProt
    Q96BY2
    Pathways
    Positive Regulation of Endopeptidase Activity
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