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NLRC4 Antikörper (C-Term)

NLRC4 Reaktivität: Human WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990417
  • Target Alle NLRC4 Antikörper anzeigen
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    Bindungsspezifität
    • 9
    • 9
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 38
    • 15
    • 6
    • 2
    Human
    Wirt
    • 26
    • 10
    • 2
    Kaninchen
    Klonalität
    • 27
    • 11
    Polyklonal
    Konjugat
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NLRC4 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 16
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Aufreinigung
    Ipaf Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Ipaf antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of human Ipaf. The immunogen is located within the last 50 amino acids of Ipaf.
    Isotyp
    IgG
    Top Product
    Discover our top product NLRC4 Primärantikörper
  • Applikationshinweise
    Ipaf polyclonal antibody can be used for the detection of Ipaf by Western blot at 1 and 2 μ,g/mL. A 110 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Ipaf Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    Ipaf antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    Andere Bezeichnung
    Ipaf (NLRC4 Produkte)
    Synonyme
    CARD12 antikoerper, CLAN antikoerper, CLAN1 antikoerper, CLANA antikoerper, CLANB antikoerper, CLANC antikoerper, CLAND antikoerper, CLR2.1 antikoerper, IPAF antikoerper, 9530011P19Rik antikoerper, Card12 antikoerper, NLR family CARD domain containing 4 antikoerper, NLR family, CARD domain containing 4 antikoerper, NLRC4 antikoerper, Nlrc4 antikoerper
    Hintergrund
    Ipaf Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and proteases including several members of the caspase family. Another family of proteins that functions as a critical regulator of apoptosis and NFκ, signaling pathways is the CED-4/Apaf-1 (apoptosis protein activating factor-1) protein family. Ipaf (ICE protease activating factor) is a CED-4/Apaf-1 family member that activates caspase-1/ICE and can induce apoptosis in human cells in a caspase-1 dependent manner. Ipaf and caspase-1 are thought to interact with each other through the association of the Ipaf amino-terminal CARD (caspase recruitment domain) and amino-terminal CARD of caspase-1.
    Molekulargewicht
    110 kDa
    Gen-ID
    58484
    NCBI Accession
    NP_067032
    UniProt
    Q9NPP4
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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