Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CUL9 Antikörper (C-Term)

CUL9 Reaktivität: Human, Maus WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990433
  • Target Alle CUL9 Antikörper anzeigen
    CUL9 (Cullin 9 (CUL9))
    Bindungsspezifität
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 18
    • 7
    • 2
    • 2
    Human, Maus
    Wirt
    • 15
    • 4
    Kaninchen
    Klonalität
    • 15
    • 4
    Polyklonal
    Konjugat
    • 19
    Dieser CUL9 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Aufreinigung
    PARC Antibody is affinity chromatography purified via peptide column.
    Immunogen
    PARC antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PARC. The immunogen is located within the last 50 amino acids of PARC.
    Isotyp
    IgG
    Top Product
    Discover our top product CUL9 Primärantikörper
  • Applikationshinweise
    PARC antibody can be used for the detection of PARC by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 1 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PARC Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    PARC antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CUL9 (Cullin 9 (CUL9))
    Andere Bezeichnung
    PARC (CUL9 Produkte)
    Synonyme
    H7AP1 antikoerper, PARC antikoerper, RP3-330M21.2 antikoerper, parc antikoerper, 1810035I07Rik antikoerper, Cul-9 antikoerper, Parc antikoerper, mKIAA0708 antikoerper, RGD1562008 antikoerper, cullin-9 antikoerper, cullin 9 antikoerper, cullin-9 antikoerper, CUL9 antikoerper, LOC100083225 antikoerper, cul9 antikoerper, LOC100561099 antikoerper, Cul9 antikoerper
    Hintergrund
    PARC Antibody: The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor. PARC, a large, Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes. In the absence of stress, PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis, while overexpression of this protein promoted cytoplasmic sequestration of p53. Surprisingly, PARC knockout mice were viable and exhibited no obvious phenotype, suggesting that other proteins, such as the highly related cullin family of E3 ubiquitin ligases, may perform similar functions in the absence of PARC. Additionally, it has been suggested that p53 binding to PARC may serve to control PARC function.
    Gen-ID
    23113
    NCBI Accession
    NP_055904
    UniProt
    Q8IWT3
Sie sind hier:
Kundenservice