TICAM2 Antikörper (C-Term)

Produktnummer ABIN6990443

Produktdetails anti-TICAM2 Antikörper

Target: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TICAM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Aufreinigung: TIRP Antibody is Ion exchange chromatography purified.

Immunogen: TIRP antibody was raised against a peptide corresponding to 16 amino acids at the C-terminus of human TIRP. The immunogen is located within the last 50 amino acids of TIRP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TIRP antibody can be used for detection of TIRP by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TIRP Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TIRP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TICAM2

Target: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Andere Bezeichnung: TIRP (TICAM2 Produkte)

Synonyme: MyD88-4 antikoerper, TICAM-2 antikoerper, TIRAP3 antikoerper, TIRP antikoerper, TRAM antikoerper, B430113A10 antikoerper, Tirp antikoerper, Trif antikoerper, toll like receptor adaptor molecule 2 antikoerper, toll-like receptor adaptor molecule 2 antikoerper, TICAM2 antikoerper, Ticam2 antikoerper

Hintergrund: TIRP Antibody: TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-κ,B. Expression of TIRP appears to be essential for TLR4 signalling.

Molekulargewicht: Predicted: 26 kDa

Observed: 27 kDa

Gen-ID: 353376

UniProt: Q86XR7

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades