TLR11 Antikörper (C-Term)

Produktnummer ABIN6990454

Produktdetails anti-TLR11 Antikörper

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Bindungsspezifität: C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Aufreinigung: TLR11 Antibody is Ion exchange chromatography purified.

Immunogen: TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of mouse TLR11. The immunogen is located within the last 50 amino acids of TLR11.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TLR11 antibody can be used for detection of TLR11 by Western blot at 0.5 to 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TLR11 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TLR11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TLR11

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Andere Bezeichnung: TLR11 (Tlr11 Produkte)

Synonyme: RGD1564460 antikoerper, Gm287 antikoerper, toll-like receptor 11 antikoerper, Tlr11 antikoerper

Hintergrund: TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

Gen-ID: 239081

NCBI Accession: NP_991388

UniProt: Q6R5P0

Pathways: Activation of Innate immune Response