Anthrax Protective Antigen Antikörper (AA 300-350)

Produktnummer ABIN6990496

Produktdetails anti-Anthrax Protective Antigen Antikörper

Target: Anthrax Protective Antigen (PA)

Bindungsspezifität: AA 300-350

Reaktivität: Bacillus anthracis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Anthrax Protective Antigen Antikörper ist unkonjugiert

Applikation: ELISA

Aufreinigung: Anthrax PA Antibody is affinity chromatography purified via peptide column.

Immunogen: Anthrax PA antibody was raised against a synthetic peptide corresponding to 16 amino acids in the middle of the Anthrax protective antigen protein. The immunogen is located within amino acids 300 - 350 of Anthrax PA .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Anthrax PA antibody can be used for the detection of Anthrax PA protein in ELISA. It will detect 10 ng of free peptide at 1 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Anthrax PA Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Anthrax PA antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Anthrax Protective Antigen

Target: Anthrax Protective Antigen (PA)

Andere Bezeichnung: Anthrax PA (PA Produkte)

Hintergrund: Anthrax PA Antibody: Anthrax infection is initiated by the inhalation, ingestion, or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF), and edema factor (EF). PA binds to two related proteins on the cell surface, these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) and capillary morphogenesis protein 2 (CMG2), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin-like protease. The bound fragment binds both LF and EF, the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm. These toxins are usually sufficient to cause rapid cell death, and often the death of the organism.

Gen-ID: 3361714

UniProt: P13423