C1QTNF2 Antikörper

Produktnummer ABIN6990599

Produktdetails anti-C1QTNF2 Antikörper

Target: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1QTNF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.

Aufreinigung: CTRP2 Antibody is affinity chromatography purified via peptide column.

Immunogen: CTRP2 antibody was raised against recombinant human CTRP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CTRP2 antibody can be used for the detection of CTRP2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CTRP2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CTRP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu C1QTNF2

Target: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Andere Bezeichnung: CTRP2 (C1QTNF2 Produkte)

Synonyme: C1QTNF2 antikoerper, fe50b04 antikoerper, wu:fe50b04 antikoerper, CTRP2 antikoerper, zacrp2 antikoerper, 1810033K05Rik antikoerper, Ctrp2 antikoerper, RGD1561041 antikoerper, C1q and tumor necrosis factor related protein 2 antikoerper, C1q and TNF related 2 antikoerper, C1QTNF2 antikoerper, c1qtnf2 antikoerper, C1qtnf2 antikoerper

Hintergrund: CTRP2 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation.

Gen-ID: 114898

NCBI Accession: NP_114114

UniProt: Q9BXJ5