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Influenza A NS1 Antikörper (C-Term)

NS1 Reaktivität: Avian Influenza Virus ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990674
  • Target Alle Influenza A NS1 (NS1) Produkte
    Influenza A NS1 (NS1) (Influenza Non Structural 1 (NS1))
    Bindungsspezifität
    • 2
    • 1
    C-Term
    Reaktivität
    • 2
    • 1
    • 1
    Avian Influenza Virus
    Wirt
    • 4
    Kaninchen
    Klonalität
    • 4
    Polyklonal
    Konjugat
    • 4
    Dieser Influenza A NS1 Antikörper ist unkonjugiert
    Applikation
    • 3
    • 1
    ELISA
    Aufreinigung
    Avian Influenza Nonstructural Protein 1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Avian Influenza Nonstructural Protein 1 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of the Avian Influenza Nonstructural Protein 1 protein. Efforts were made to use relatively conserved regions of the viral sequence as the antigen. The immunogen is located within the last 50 amino acids of Avian Influenza Nonstructural Protein 1.
    Isotyp
    IgG
  • Applikationshinweise
    Avian Influenza Nonstructural Protein 1 antibody can be used for the detection of the avian influenza nonstructural protein 1 protein from influenza A in ELISA.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Avian Influenza Nonstructural Protein 1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    Avian Influenza Nonstructural Protein 1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    Influenza A NS1 (NS1) (Influenza Non Structural 1 (NS1))
    Andere Bezeichnung
    Avian Influenza Nonstructural Protein 1 (NS1 Produkte)
    Synonyme
    nonstructural protein 1 antikoerper, NS1 antikoerper
    Substanzklasse
    Influenza Protein
    Hintergrund
    Avian Influenza Nonstructural Protein 1 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however, it is in birds that all subtypes, including the so-called "avian flu" or H5N1, can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2'-5'OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.
    UniProt
    Q2L6Z3
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