Influenza A NS1 Antikörper (C-Term)

Produktnummer ABIN6990674

Produktdetails anti-Influenza A NS1 Antikörper

Target: Influenza A NS1 (NS1) (Influenza Non Structural 1 (NS1))

Bindungsspezifität: C-Term

Reaktivität: Avian Influenza Virus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Influenza A NS1 Antikörper ist unkonjugiert

Applikation: ELISA

Aufreinigung: Avian Influenza Nonstructural Protein 1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Avian Influenza Nonstructural Protein 1 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of the Avian Influenza Nonstructural Protein 1 protein. Efforts were made to use relatively conserved regions of the viral sequence as the antigen. The immunogen is located within the last 50 amino acids of Avian Influenza Nonstructural Protein 1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Avian Influenza Nonstructural Protein 1 antibody can be used for the detection of the avian influenza nonstructural protein 1 protein from influenza A in ELISA.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Avian Influenza Nonstructural Protein 1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Avian Influenza Nonstructural Protein 1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Influenza A NS1

Target: Influenza A NS1 (NS1) (Influenza Non Structural 1 (NS1))

Andere Bezeichnung: Avian Influenza Nonstructural Protein 1 (NS1 Produkte)

Synonyme: nonstructural protein 1 antikoerper, NS1 antikoerper

Substanzklasse: Influenza Protein

Hintergrund: Avian Influenza Nonstructural Protein 1 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however, it is in birds that all subtypes, including the so-called "avian flu" or H5N1, can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2'-5'OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.

UniProt: Q2L6Z3