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ARHGEF17 Antikörper (AA 910-960)

ARHGEF17 Reaktivität: Human ELISA, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990812
  • Target Alle ARHGEF17 Antikörper anzeigen
    ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))
    Bindungsspezifität
    • 1
    • 1
    • 1
    • 1
    AA 910-960
    Reaktivität
    • 11
    • 9
    Human
    Wirt
    • 11
    Kaninchen
    Klonalität
    • 11
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARHGEF17 Antikörper ist unkonjugiert
    Applikation
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    TEM4 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    TEM4 antibody was raised against a 18 amino acid synthetic peptide near the center of human TEM4. The immunogen is located within amino acids 910 - 960 of TEM4.
    Isotyp
    IgG
    Top Product
    Discover our top product ARHGEF17 Primärantikörper
  • Applikationshinweise
    TEM4 antibody can be used for detection of TEM4 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    TEM4 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    TEM4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))
    Andere Bezeichnung
    TEM4 (ARHGEF17 Produkte)
    Synonyme
    P164RHOGEF antikoerper, TEM4 antikoerper, p164-RhoGEF antikoerper, 8030463K16 antikoerper, AI428794 antikoerper, AW558066 antikoerper, BC035332 antikoerper, mKIAA0337 antikoerper, Rho guanine nucleotide exchange factor 17 antikoerper, Rho guanine nucleotide exchange factor (GEF) 17 antikoerper, ARHGEF17 antikoerper, Arhgef17 antikoerper
    Hintergrund
    TEM4 Antibody: Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.
    Molekulargewicht
    Predicted: 220 kDa

    Observed: 200 kDa
    Gen-ID
    9828
    UniProt
    Q96PE2
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