DLGAP3 Antikörper (C-Term)

Produktnummer ABIN6990832

Produktdetails anti-DLGAP3 Antikörper

Target: DLGAP3 (Discs, Large (Drosophila) Homolog-Associated Protein 3 (DLGAP3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLGAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: SAPAP3 Antibody is affinity chromatography purified via peptide column.

Immunogen: SAPAP3 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human SAPAP3. The immunogen is located within the last 50 amino acids of SAPAP3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SAPAP3 antibody can be used for detection of SAPAP3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SAPAP3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SAPAP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DLGAP3

Target: DLGAP3 (Discs, Large (Drosophila) Homolog-Associated Protein 3 (DLGAP3))

Andere Bezeichnung: SAPAP3 (DLGAP3 Produkte)

Synonyme: DAP3 antikoerper, SAPAP3 antikoerper, BC058433 antikoerper, DAP-3 antikoerper, Prpl8 antikoerper, Sapap3 antikoerper, Dap3 antikoerper, DLG associated protein 3 antikoerper, discs, large (Drosophila) homolog-associated protein 3 antikoerper, DLGAP3 antikoerper, Dlgap3 antikoerper, dlgap3 antikoerper

Hintergrund: SAPAP3 Antibody: SAP90/PSD-95-associated protein 3 (SAPAP3, also known as DLGAP3) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP3 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). Both SAPAP3 protein and mRNA are targeted to dendrites, whereas SAPAP1, -2, and -4 mRNAs are detected mainly in cell bodies. Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD), as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice. At least two isoforms are known to exist.

Gen-ID: 58512

UniProt: O95886