PLXDC2 Antikörper (N-Term)

Produktnummer ABIN6990835

Produktdetails anti-PLXDC2 Antikörper

Target: PLXDC2 (Plexin Domain Containing 2 (PLXDC2))

Bindungsspezifität: AA 40-90, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLXDC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: Plxdc2 Antibody is affinity chromatography purified via peptide column.

Immunogen: Plxdc2 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human Plxdc2. The immunogen is located within amino acids 40 - 90 of Plxdc2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Plxdc2 antibody can be used for detection of Plxdc2 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Plxdc2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Plxdc2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PLXDC2

Target: PLXDC2 (Plexin Domain Containing 2 (PLXDC2))

Andere Bezeichnung: Plxdc2 (PLXDC2 Produkte)

Synonyme: MGC79122 antikoerper, TEM7R antikoerper, 1200007L24Rik antikoerper, 5430431D22Rik antikoerper, AI646728 antikoerper, AU022916 antikoerper, AV231634 antikoerper, Tem7r antikoerper, plexin domain containing 2 antikoerper, plexin domain containing 2 L homeolog antikoerper, PLXDC2 antikoerper, plxdc2.L antikoerper, plxdc2 antikoerper, Plxdc2 antikoerper

Hintergrund: Plxdc2 Antibody: Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57 % amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.

Molekulargewicht: Predicted: 55 kDa

Observed: 55 kDa

Gen-ID: 84898

UniProt: Q6UX71