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RIMS2 Antikörper (AA 30-80)
RIMS2
Reaktivität: Human
ELISA, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN6990845
Produktdetails anti-RIMS2 Antikörper
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Target
Alle RIMS2 Antikörper anzeigen
RIMS2
(Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
Bindungsspezifität
Alle Epitope für RIMS2 Antikörper
AA 30-80
Reaktivität
Alle Reaktivitäten für RIMS2 Antikörper
Human
Wirt
Alle Wirte für RIMS2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für RIMS2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für RIMS2 Antikörper
Dieser RIMS2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für RIMS2 Antikörper
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
RIM2 Antibody is affinity chromatography purified via peptide column.
Immunogen
RIM2 antibody was raised against a 16 amino acid peptide near the carboxy terminusof human RIM2. The immunogen is located within amino acids 30 - 80 of RIM2.
Isotyp
IgG
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Anwendungsinformationen
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Applikationshinweise
RIM2 antibody can be used for detection of RIM2 by immunohistochemistry at 5 μ,g/mL. Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
RIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
RIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu RIMS2
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Target
RIMS2
(Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
Andere Bezeichnung
RIM2 (RIMS2 Produkte )
Synonyme
OBOE antikoerper, RAB3IP3 antikoerper, RIM2 antikoerper, 2810036I15Rik antikoerper, AW048769 antikoerper, Rab3ip2 antikoerper, Rim2(+40A) antikoerper, Rim2(+44A) antikoerper, Rim2(+4A) antikoerper, Serg2 antikoerper, Syt3-rs antikoerper, mKIAA0751 antikoerper, Nim2 antikoerper, Rim2 antikoerper, RIMS2 antikoerper, MGC159469 antikoerper, rims2 antikoerper, zgc:73064 antikoerper, drs antikoerper, drsp antikoerper, mema antikoerper, np-a antikoerper, pinin antikoerper, pnn antikoerper, pnn-a antikoerper, pnn-b antikoerper, sdk3 antikoerper, regulating synaptic membrane exocytosis 2 antikoerper, regulating synaptic membrane exocytosis 2a antikoerper, pinin, desmosome associated protein S homeolog antikoerper, RIMS2 antikoerper, Rims2 antikoerper, rims2a antikoerper, pnn.S antikoerper
Hintergrund
RIM2 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. RIM1 and RIM2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release, synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like RIM1, RIM2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.
Molekulargewicht
Predicted: 148 kDa
Gen-ID
9699
NCBI Accession
NP_001093587
UniProt
Q9UQ26
Pathways
Hormone Transport , Synaptic Vesicle Exocytosis
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