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AIFM3 Antikörper (AA 210-260)

AIFM3 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990881
  • Target Alle AIFM3 Antikörper anzeigen
    AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-260
    Reaktivität
    • 15
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 14
    • 1
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AIFM3 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    AIFM3 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    AIFM3 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AIFM3. The immunogen is located within amino acids 210 - 260 of AIFM3.
    Isotyp
    IgG
    Top Product
    Discover our top product AIFM3 Primärantikörper
  • Applikationshinweise
    AIFM3 antibody can be used for the detection of AIFM3 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    AIFM3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    AIFM3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
    Andere Bezeichnung
    AIFM3 (AIFM3 Produkte)
    Synonyme
    nfrl-A antikoerper, MGC84340 antikoerper, AIFM3 antikoerper, LOC100150876 antikoerper, 2810401C16Rik antikoerper, AI840249 antikoerper, Aifl antikoerper, RGD1306028 antikoerper, AIFL antikoerper, apoptosis inducing factor, mitochondria associated 3 L homeolog antikoerper, apoptosis inducing factor, mitochondria associated 3 antikoerper, apoptosis-inducing factor, mitochondrion-associated 3 antikoerper, aifm3.L antikoerper, AIFM3 antikoerper, aifm3 antikoerper, Aifm3 antikoerper
    Hintergrund
    AIFM3 Antibody: Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist.
    Gen-ID
    150209
    UniProt
    Q96NN9
    Pathways
    Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis
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