At least three isoforms of GRTP1 are known to exist, this antibody should recognize all isoforms.
Aufreinigung
GRTP1 Antibody is affinity chromatography purified via peptide column.
Immunogen
GRTP1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human GRTP1. The immunogen is located within amino acids 80 - 130 of GRTP1.
GRTP1
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
GRTP1 antibody can be used for detection of GRTP1 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
GRTP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
GRTP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
GRTP1
(Growth Hormone Regulated TBC Protein 1 (GRTP1))
GRTP1 Antibody: Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment.