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VPS53 Antikörper (AA 390-440)

VPS53 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990901
  • Target Alle VPS53 Antikörper anzeigen
    VPS53 (Vacuolar Protein Sorting 53 Homolog (VPS53))
    Bindungsspezifität
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 390-440
    Reaktivität
    • 20
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 18
    • 2
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VPS53 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    VPS53 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    VPS53 antibody was raised against a 18 amino acid synthetic peptide from near the center of human VPS53. The immunogen is located within amino acids 390 - 440 of VPS53.
    Isotyp
    IgG
    Top Product
    Discover our top product VPS53 Primärantikörper
  • Applikationshinweise
    VPS53 antibody can be used for detection of VPS53 by Western blot at 0.5 - 1 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    VPS53 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    VPS53 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    VPS53 (Vacuolar Protein Sorting 53 Homolog (VPS53))
    Andere Bezeichnung
    VPS53 (VPS53 Produkte)
    Synonyme
    wu:fb77d11 antikoerper, zgc:103741 antikoerper, DKFZp469N152 antikoerper, 2010002A08Rik antikoerper, 2310040I21Rik antikoerper, 3100002B05Rik antikoerper, Hccs1 antikoerper, HCCS1 antikoerper, hVps53L antikoerper, pp13624 antikoerper, RGD1311391 antikoerper, VPS53, GARP complex subunit antikoerper, vacuolar protein sorting 53 homolog (S. cerevisiae) antikoerper, vacuolar protein sorting 53 antikoerper, VPS53 GARP complex subunit antikoerper, VPS53 antikoerper, vps53 antikoerper, PAAG_00802 antikoerper, MCYG_06020 antikoerper, VDBG_07188 antikoerper, MGYG_05943 antikoerper, Vps53 antikoerper
    Hintergrund
    VPS53 Antibody: The sorting of acid hydrolases to lysosomes rely on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes. The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex which is composed of three subunits: VPS52, VPS53, and VPS54. Depletion of any of these three proteins, such as by RNAi, impairs the retrograde transport of multiple TGN proteins. VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry to the cell, suggesting that VPS53 may be an important drug target in HIV treatment. At least five isoforms of VPS53 are known to exist.
    Gen-ID
    55275
    UniProt
    Q5VIR6
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