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BICD1 Antikörper (C-Term)

BICD1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990932
  • Target Alle BICD1 Antikörper anzeigen
    BICD1 (Bicaudal D Homolog 1 (BICD1))
    Bindungsspezifität
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 14
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 13
    • 1
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BICD1 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    At least two isoforms of BICD1 are known to exist, this antibody will only recognize the larger isoform.
    Aufreinigung
    BICD1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    BICD1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human BICD1. The immunogen is located within the last 50 amino acids of BICD1.
    Isotyp
    IgG
    Top Product
    Discover our top product BICD1 Primärantikörper
  • Applikationshinweise
    BICD1 antibody can be used for detection of BICD1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    BICD1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    BICD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    BICD1 (Bicaudal D Homolog 1 (BICD1))
    Andere Bezeichnung
    BICD1 (BICD1 Produkte)
    Synonyme
    BICD antikoerper, B830009D06Rik antikoerper, mKIAA4125 antikoerper, bicaudal D homolog 1 L homeolog antikoerper, BICD cargo adaptor 1 antikoerper, bicaudal D homolog 1 (Drosophila) antikoerper, bicd1.L antikoerper, BICD1 antikoerper, Bicd1 antikoerper
    Hintergrund
    BICD1 Antibody: BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells.
    Gen-ID
    636
    NCBI Accession
    NP_001705
    UniProt
    Q96G01
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, Maintenance of Protein Location
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