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CNOT4 Antikörper (N-Term)

CNOT4 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990985
  • Target Alle CNOT4 Antikörper anzeigen
    CNOT4 (CCR4-NOT Transcription Complex Subunit 4 (CNOT4))
    Bindungsspezifität
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-120, N-Term
    Reaktivität
    • 44
    • 20
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Human, Maus, Ratte
    Wirt
    • 33
    • 11
    Kaninchen
    Klonalität
    • 33
    • 11
    Polyklonal
    Konjugat
    • 27
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CNOT4 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 21
    • 11
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    CNOT4 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    CNOT4 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of the human CNOT4. The immunogen is located within amino acids 70 - 120 of CNOT4.
    Isotyp
    IgG
    Top Product
    Discover our top product CNOT4 Primärantikörper
  • Applikationshinweise
    CNOT4 antibody can be used for detection of CNOT4 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    CNOT4 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    CNOT4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CNOT4 (CCR4-NOT Transcription Complex Subunit 4 (CNOT4))
    Andere Bezeichnung
    CNOT4 (CNOT4 Produkte)
    Synonyme
    CLONE243 antikoerper, NOT4 antikoerper, NOT4H antikoerper, Not4 antikoerper, Not4h antikoerper, Not4hp antikoerper, CNOT4 antikoerper, CCR4-NOT transcription complex subunit 4 antikoerper, RNA binding (RRM/RBD/RNP motifs) family protein antikoerper, CCR4-NOT transcription complex, subunit 4 antikoerper, CCR4-NOT transcription complex subunit 4 L homeolog antikoerper, CCR4-NOT transcription complex, subunit 4b antikoerper, CNOT4 antikoerper, AT3G45630 antikoerper, Cnot4 antikoerper, cnot4.L antikoerper, cnot4b antikoerper
    Hintergrund
    CNOT4 Antibody: CNOT4 is a component of the CCR4-NOT transcription complex, a complex that is implicated in the repression of RNA polymerase II transcription. In the CCR4-NOT complex, CNOT4 acts as an E3 ubiquitin-protein ligase and interacts with a subset of E2 ubiquitin-conjugating enzymes through a unique C4C4 RING domain. This E3 ligase activity was shown to be dependent on the selective and specific interaction with the ubiquitin conjugating enzyme UbcH5B. In yeast, mutations in CNOT4 that prevented its interaction with the UbcH5B homolog UBC4 caused increased sensitivity to hydroxyurea, heat shock, and hygromycin B, suggesting that CNOT4 and UbcH5B are involved in stress response in vivo. Multiple isoforms of CNOT4 are known to exist.
    Gen-ID
    4850
    NCBI Accession
    NP_037448
    UniProt
    O95628
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