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SPRED1 Antikörper (AA 250-300)

SPRED1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990996
  • Target Alle SPRED1 Antikörper anzeigen
    SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))
    Bindungsspezifität
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-300
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 37
    • 7
    Kaninchen
    Klonalität
    • 37
    • 7
    Polyklonal
    Konjugat
    • 20
    • 6
    • 5
    • 5
    • 4
    • 4
    Dieser SPRED1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 33
    • 20
    • 7
    • 6
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Spezifität
    This Spred1 antibody is predicted to have no cross-reactivity to Spred2 or Spred3.
    Aufreinigung
    Spred1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Spred1 antibody was raised against a 14 amino acid synthetic peptide near the center of the human Spred1. The immunogen is located within amino acids 250 - 300 of Spred1.
    Isotyp
    IgG
    Top Product
    Discover our top product SPRED1 Primärantikörper
  • Applikationshinweise
    Spred1 antibody can be used for detection of Spred1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Spred1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    Spred1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))
    Andere Bezeichnung
    Spred1 (SPRED1 Produkte)
    Synonyme
    fb14c08 antikoerper, fj51c03 antikoerper, zgc:85707 antikoerper, wu:fb14c08 antikoerper, wu:fj51c03 antikoerper, Xspred1 antikoerper, Xtspred1 antikoerper, 5730461F13Rik antikoerper, AL024345 antikoerper, AW047647 antikoerper, NFLS antikoerper, hSpred1 antikoerper, spred-1 antikoerper, sprouty-related, EVH1 domain containing 1 antikoerper, sprouty related EVH1 domain containing 1 antikoerper, sprouty related, EVH1 domain containing 1 antikoerper, sprouty related, EVH1 domain containing 1 L homeolog antikoerper, SPRED1 antikoerper, sprouty protein with EVH-1 domain 1, related sequence antikoerper, spred1 antikoerper, SPRED1 antikoerper, spred1.L antikoerper, Bm1_51610 antikoerper, Spred1 antikoerper
    Hintergrund
    Spred1 Antibody: The Ras-MAP kinase pathway is essential for the differentiation of neuronal cells and myocytes, it is inhibited by Spred1, a member of the Sprouty family of proteins. Spred1 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).
    Molekulargewicht
    Predicted: 49 kDa

    Observed: 498 kDa
    Gen-ID
    161742
    NCBI Accession
    NP_689807
    UniProt
    Q7Z699
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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