Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This MettL7B antibody is predicted to not cross-react with MettL7A.
Aufreinigung
MettL7B Antibody is affinity chromatography purified via peptide column.
Immunogen
MettL7B antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human MettL7B. The immunogen is located within the last 50 amino acids of MettL7B.
METTL7B
Reaktivität: Human, Maus
WB, ELISA
Wirt: Kaninchen
Polyclonal
PE
Applikationshinweise
MettL7B antibody can be used for detection of Mettl7B by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
MettL7B Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
MettL7B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ALDI antikoerper, 0610006F02Rik antikoerper, AI266817 antikoerper, RGD1305205 antikoerper, methyltransferase like 7B antikoerper, METTL7B antikoerper, Mettl7b antikoerper
Hintergrund
MettL7B Antibody: MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.