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Junctophilin 1 Antikörper (C-Term)

JPH1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991017
  • Target Alle Junctophilin 1 (JPH1) Antikörper anzeigen
    Junctophilin 1 (JPH1)
    Bindungsspezifität
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 470-520, C-Term
    Reaktivität
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    Human, Maus, Ratte
    Wirt
    • 12
    • 3
    Kaninchen
    Klonalität
    • 13
    • 2
    Polyklonal
    Konjugat
    • 11
    • 2
    • 1
    • 1
    Dieser Junctophilin 1 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    JPH1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    JPH1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human JPH1. The immunogen is located within amino acids 470 - 520 of JPH1.
    Isotyp
    IgG
    Top Product
    Discover our top product JPH1 Primärantikörper
  • Applikationshinweise
    JPH1 antibody can be used for detection of JPH1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    JPH1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    JPH1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    Junctophilin 1 (JPH1)
    Andere Bezeichnung
    JPH1 (JPH1 Produkte)
    Synonyme
    JP-1 antikoerper, JP1 antikoerper, ENSMUSG00000054314 antikoerper, Jp1 antikoerper, bZ1M12.3 antikoerper, jph1 antikoerper, si:rp71-1m12.3 antikoerper, Jph1 antikoerper, junctophilin 1 antikoerper, junctophilin 1a antikoerper, junctophilin-1 antikoerper, JPH1 antikoerper, Jph1 antikoerper, jph1 antikoerper, jph1a antikoerper, LOC100547979 antikoerper
    Hintergrund
    JPH1 Antibody: Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain and contribute to the subsurface cistern formation in neurons. JPH1 is essential for stabilizing the T-tubule and SR membranes to form junctions and provide an environment for the assembly of receptors such as the ryanodine receptor type 1 (RyR1).
    Gen-ID
    56704
    UniProt
    Q9HDC5
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