TOM70 Antikörper (AA 220-270)

Produktnummer ABIN6991035

Produktdetails anti-TOM70 Antikörper

Target: TOM70 (TOMM70A) (Translocase of Outer Mitochondrial Membrane 70 (TOMM70A))

Bindungsspezifität: AA 220-270

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOM70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: TOM70 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-TOM70 antibody was raised against a peptide corresponding to 15 amino acids near the center of human TOM70. The immunogen is located within amino acids 220-270 of TOM70.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μ,g/mL, IHC: 2.5 μ,g/mL, IF: 20 μ,g/mL.

Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TOM70 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TOM70 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TOM70

Target: TOM70 (TOMM70A) (Translocase of Outer Mitochondrial Membrane 70 (TOMM70A))

Andere Bezeichnung: TOM70 (TOMM70A Produkte)

Synonyme: MGC68780 antikoerper, TOMM70A antikoerper, Tom70 antikoerper, KIAA0719 antikoerper, MGC73188 antikoerper, zgc:73188 antikoerper, wu:fj58b04 antikoerper, CG6756 antikoerper, Dmel\\CG6756 antikoerper, dtom70 antikoerper, GB13743 antikoerper, TOM70 antikoerper, 2610044B22Rik antikoerper, D16Ium22 antikoerper, D16Ium22e antikoerper, D16Wsu109e antikoerper, mKIAA0719 antikoerper, to translocase of outer mitochondrial membrane 70 S homeolog antikoerper, translocase of outer mitochondrial membrane 70 antikoerper, translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) antikoerper, Translocase of outer membrane 70 antikoerper, mitochondrial import receptor subunit TOM70 antikoerper, translocase of outer mitochondrial membrane 70 homolog A (yeast) antikoerper, tomm70.S antikoerper, TOMM70 antikoerper, tomm70a antikoerper, tomm70 antikoerper, Tom70 antikoerper, LOC726081 antikoerper, Tomm70 antikoerper, Tomm70a antikoerper

Hintergrund: TOM70 Antibody: The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria. TOM70, an important member of the TOM complex, contains a tetratricopeptide repeat domain similar to those found in cytosolic chaperones such as Hsp90 and Hsc70 and provides a docking site for these proteins. This interaction is thought to be a critical first step in the TOM70-dependent mitochondrial import, followed by contact between the preprotein and TOM70. After targeting to TOM70, preproteins are translocated through the outer membrane via the TOM40 import pore complex. The precise mechanism of how preproteins progress from TOM70 to TOM40 to full translocation is still unclear. At least two isoforms of TOM70 are known to exist.

Molekulargewicht: Predicted: 68kD

Observed: 72 kD kDa

Gen-ID: 9868

NCBI Accession: NP_055635

UniProt: O94826

Pathways: SARS-CoV-2 Protein Interaktom