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RCAN2 Antikörper (AA 70-120)

RCAN2 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991070
  • Target Alle RCAN2 Antikörper anzeigen
    RCAN2 (Regulator of Calcineurin 2 (RCAN2))
    Bindungsspezifität
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-120
    Reaktivität
    • 28
    • 19
    • 12
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 26
    • 2
    Kaninchen
    Klonalität
    • 28
    Polyklonal
    Konjugat
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RCAN2 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 12
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Aufreinigung
    RCAN2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    RCAN2 antibody was raised against a 14 amino acid synthetic peptide near the center of human RCAN2. The immunogen is located within amino acids 70 - 120 of RCAN2.
    Isotyp
    IgG
    Top Product
    Discover our top product RCAN2 Primärantikörper
  • Applikationshinweise
    RCAN2 antibody can be used for detection of RCAN2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    RCAN2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    RCAN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    RCAN2 (Regulator of Calcineurin 2 (RCAN2))
    Andere Bezeichnung
    RCAN2 (RCAN2 Produkte)
    Synonyme
    DSCR1L1 antikoerper, si:ch211-124g24.1 antikoerper, zgc:85746 antikoerper, RCAN2 antikoerper, DKFZp459H071 antikoerper, rcan2 antikoerper, CSP2 antikoerper, MCIP2 antikoerper, RCN2 antikoerper, ZAKI-4 antikoerper, ZAKI4 antikoerper, Csp2 antikoerper, Dscr1l1 antikoerper, Dcip2 antikoerper, Zaki-4 antikoerper, regulator of calcineurin 2 antikoerper, rcan2 antikoerper, RCAN2 antikoerper, Rcan2 antikoerper
    Hintergrund
    RCAN2 Antibody: Regulator of calcineurin 2 (RCAN2), also known as ZAKI4 and DSCR1L1, is expressed as two isoforms differing at their N-terminus. The longer of the two (isoform 1) is expressed exclusively in the brain, while isoform 2 is ubiquitously expressed, with highest expression in brain, heart, and muscle. Both isoforms bind to the catalytic subunit of calcineurin, a Ca++-dependent protein phosphatase involved in several neuronal functions, though their C-terminal region and inhibit calcineurin's activity. Unlike isoform 1 of RCAN2, the expression of the second isoform is not induced by the thyroid hormone T3. RCAN2 is a member of a family of three endogenous calcineurin regulators that are located near the minimal supernumerary fragment of chromosome 21 in individuals with Down syndrome, suggesting that they play a role in this syndrome. Multiple isoforms of RCAN2 are known to exist.
    Gen-ID
    53901
    UniProt
    Q9JHG2
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