PCDH12 Antikörper (N-Term)

Produktnummer ABIN6991078

Produktdetails anti-PCDH12 Antikörper

Target: PCDH12 (Protocadherin 12 (PCDH12))

Bindungsspezifität: AA 30-80, N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDH12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody is predicted to not cross-react with PCDH18.

Aufreinigung: PCDH12 Antibody is affinity chromatography purified via peptide column.

Immunogen: PCDH12 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human PCDH12. The immunogen is located within amino acids 30 - 80 of PCDH12.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PCDH12 antibody can be used for detection of PCDH12 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PCDH12 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PCDH12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PCDH12

Target: PCDH12 (Protocadherin 12 (PCDH12))

Andere Bezeichnung: PCDH12 (PCDH12 Produkte)

Synonyme: PCDH12 antikoerper, VE-cadherin-2 antikoerper, VECAD2 antikoerper, Pcdh14 antikoerper, VE-cad-2 antikoerper, protocadherin 12 antikoerper, PCDH12 antikoerper, Pcdh12 antikoerper

Hintergrund: PCDH12 Antibody: Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA, further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.

Molekulargewicht: Predicted: 128 kDa

Observed: 125 kDa

Gen-ID: 51294

NCBI Accession: NP_057664

UniProt: Q9NPG4

Pathways: Cellular Glucan Metabolic Process