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ST3GAL6 Antikörper (C-Term)

ST3GAL6 Reaktivität: Human, Maus, Ratte WB, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991119
  • Target Alle ST3GAL6 Antikörper anzeigen
    ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))
    Bindungsspezifität
    AA 230-280, C-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 1
    Kaninchen
    Klonalität
    • 1
    Polyklonal
    Konjugat
    • 1
    Dieser ST3GAL6 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Aufreinigung
    ST3gal6 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    ST3gal6 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ST3gal6. The immunogen is located within amino acids 230 - 280 of ST3gal6.
    Isotyp
    IgG
    Top Product
    Discover our top product ST3GAL6 Primärantikörper
  • Applikationshinweise
    ST3gal6 antibody can be used for detection of ST3gal6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    ST3gal6 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    ST3gal6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))
    Andere Bezeichnung
    ST3gal6 (ST3GAL6 Produkte)
    Synonyme
    SIAT10 antikoerper, ST3GALVI antikoerper, 1700023B24Rik antikoerper, AI930218 antikoerper, AW552396 antikoerper, Siat10 antikoerper, St3galVI antikoerper, ST3GAL-VI antikoerper, ST3 beta-galactoside alpha-2,3-sialyltransferase 6 antikoerper, ST3GAL6 antikoerper, St3gal6 antikoerper
    Hintergrund
    ST3gal6 Antibody: Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.
    Gen-ID
    10402
    NCBI Accession
    NP_006091
    UniProt
    Q9Y274
    Pathways
    Glycosaminoglycan Metabolic Process
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