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JMJD1C Antikörper (N-Term)

JMJD1C Reaktivität: Human, Maus, Ratte ELISA, WB, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991178
  • Target Alle JMJD1C Antikörper anzeigen
    JMJD1C (Jumonji Domain Containing 1C (JMJD1C))
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 380-430, N-Term
    Reaktivität
    • 13
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 10
    • 3
    Kaninchen
    Klonalität
    • 10
    • 3
    Polyklonal
    Konjugat
    • 9
    • 2
    • 1
    • 1
    Dieser JMJD1C Antikörper ist unkonjugiert
    Applikation
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Spezifität
    This antibody will not cross-react with JMJD1A or JMJD1B.
    Aufreinigung
    JMJD1C Antibody is affinity chromatography purified via peptide column.
    Immunogen
    JMJD1C antibody was raised against a 20 amino acid synthetic peptide from near the amino terminus of human JMJD1C. The immunogen is located within amino acids 380 - 430 of JMJD1C.
    Isotyp
    IgG
    Top Product
    Discover our top product JMJD1C Primärantikörper
  • Applikationshinweise
    JMJD1C antibody can be used for detection of JMJD1C by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    JMJD1C Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    JMJD1C antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    JMJD1C (Jumonji Domain Containing 1C (JMJD1C))
    Andere Bezeichnung
    JMJD1C (JMJD1C Produkte)
    Synonyme
    RP11-10C13.2 antikoerper, TRIP8 antikoerper, 5430433L24Rik antikoerper, D630035I23Rik antikoerper, Jmjdic antikoerper, Pr2 antikoerper, JMJD1C antikoerper, DKFZp469A034 antikoerper, jumonji domain containing 1C antikoerper, JMJD1C antikoerper, Jmjd1c antikoerper, jmjd1c antikoerper
    Hintergrund
    JMJD1C Antibody: The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.
    Gen-ID
    221037
    NCBI Accession
    NP_116165
    UniProt
    Q15652
    Pathways
    Nuclear Hormone Receptor Binding
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