INSM1 Antikörper (N-Term)

Produktnummer ABIN6991197

Produktdetails anti-INSM1 Antikörper

Target: INSM1 (Insulinoma-Associated 1 (INSM1))

Bindungsspezifität: AA 90-140, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INSM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: IA-1 Antibody is affinity chromatography purified via peptide column.

Immunogen: IA-1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human IA-1. The immunogen is located within amino acids 90 - 140 of IA-1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IA-1 antibody can be used for detection of IA-1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IA-1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IA-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu INSM1

Target: INSM1 (Insulinoma-Associated 1 (INSM1))

Andere Bezeichnung: IA-1 (INSM1 Produkte)

Synonyme: IA-1 antikoerper, IA1 antikoerper, INSM-1 antikoerper, Insm1 antikoerper, fc13a09 antikoerper, wu:fc13a09 antikoerper, zINSM-1 antikoerper, zgc:63866 antikoerper, INSM1 antikoerper, ia-1 antikoerper, zgc:77257 antikoerper, INSM transcriptional repressor 1 antikoerper, insulinoma-associated 1 antikoerper, insulinoma-associated 1b antikoerper, insulinoma associated 1 antikoerper, insulinoma associated 1 L homeolog antikoerper, insulinoma-associated 1a antikoerper, INSM1 antikoerper, Insm1 antikoerper, insm1b antikoerper, insm1 antikoerper, insm1.L antikoerper, insm1a antikoerper

Hintergrund: IA-1 Antibody: IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100 % of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.

Gen-ID: 3642

NCBI Accession: NP_002187

UniProt: Q01101