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TMEM38A Antikörper (C-Term)

TMEM38A Reaktivität: Human, Ratte, Maus WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991239
  • Target Alle TMEM38A Antikörper anzeigen
    TMEM38A (Transmembrane Protein 38A (TMEM38A))
    Bindungsspezifität
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 8
    • 1
    Kaninchen
    Klonalität
    • 9
    Polyklonal
    Konjugat
    • 9
    Dieser TMEM38A Antikörper ist unkonjugiert
    Applikation
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Aufreinigung
    TMEM38A Antibody is affinity chromatography purified via peptide column.
    Immunogen
    TMEM38A antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human TMEM38A. The immunogen is located within the last 50 amino acids of TMEM38A.
    Isotyp
    IgG
    Top Product
    Discover our top product TMEM38A Primärantikörper
  • Applikationshinweise
    TMEM38A antibody can be used for detection of TMEM38A by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    TMEM38A Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    TMEM38A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    TMEM38A (Transmembrane Protein 38A (TMEM38A))
    Andere Bezeichnung
    TMEM38A (TMEM38A Produkte)
    Synonyme
    zgc:77831 antikoerper, MGC75707 antikoerper, TMEM38A antikoerper, TRIC-A antikoerper, TRICA antikoerper, 1110001E17Rik antikoerper, AI413399 antikoerper, mg33a antikoerper, RGD1307901 antikoerper, Srp-27 antikoerper, transmembrane protein 38A antikoerper, transmembrane protein 38a antikoerper, transmembrane protein 38A L homeolog antikoerper, tmem38a antikoerper, CpipJ_CPIJ011791 antikoerper, CpipJ_CPIJ013655 antikoerper, TMEM38A antikoerper, Tmem38a antikoerper, tmem38a.L antikoerper
    Hintergrund
    TMEM38A Antibody: TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure, the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.
    Gen-ID
    79041
    UniProt
    Q9H6F2
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