KCNK18 Antikörper (AA 210-260)

Produktnummer ABIN6991251

Produktdetails anti-KCNK18 Antikörper

Target: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Bindungsspezifität: AA 210-260

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNK18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: TRESK Antibody is affinity chromatography purified via peptide column.

Immunogen: TRESK antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRESK. The immunogen is located within amino acids 210 - 260 of TRESK.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TRESK antibody can be used for detection of TRESK by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TRESK Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TRESK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu KCNK18

Target: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Andere Bezeichnung: TRESK (KCNK18 Produkte)

Synonyme: K2p18.1 antikoerper, MGR13 antikoerper, TRESK antikoerper, TRESK-2 antikoerper, TRESK2 antikoerper, TRIK antikoerper, Gm781 antikoerper, Tresk antikoerper, Tresk-2 antikoerper, Trik antikoerper, potassium two pore domain channel subfamily K member 18 antikoerper, potassium channel, subfamily K, member 18 antikoerper, KCNK18 antikoerper, Kcnk18 antikoerper

Hintergrund: TRESK Antibody: TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.

Gen-ID: 338567

NCBI Accession: NP_862823

UniProt: Q7Z418