ARHGAP18 Antikörper (C-Term)

Produktnummer ABIN6991267

Produktdetails anti-ARHGAP18 Antikörper

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Aufreinigung: ARHGAP18 Antibody is affinity chromatography purified via peptide column.

Immunogen: ARHGAP18 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ARHGAP18. The immunogen is located within the last 50 amino acids of ARHGAP18.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ARHGAP18 antibody can be used for detection of ARHGAP18 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ARHGAP18 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ARHGAP18 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ARHGAP18

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Andere Bezeichnung: ARHGAP18 (ARHGAP18 Produkte)

Synonyme: 4833419J07Rik antikoerper, AI314906 antikoerper, AI843501 antikoerper, MacGAP antikoerper, SENEX antikoerper, bA307O14.2 antikoerper, MGC146282 antikoerper, DKFZp469I1011 antikoerper, Rho GTPase activating protein 18 antikoerper, Rho GTPase activating protein 18 L homeolog antikoerper, Arhgap18 antikoerper, ARHGAP18 antikoerper, arhgap18 antikoerper, arhgap18.L antikoerper

Hintergrund: ARHGAP18 Antibody: ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.

Gen-ID: 93663

NCBI Accession: NP_277050

UniProt: Q8N392