LZTR1 Antikörper (N-Term)

Produktnummer ABIN6991281

Produktdetails anti-LZTR1 Antikörper

Target: LZTR1 (Leucine-Zipper-Like Transcription Regulator 1 (LZTR1))

Bindungsspezifität: AA 130-180, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LZTR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: LZTR1 Antibody is affinity chromatography purified via peptide column.

Immunogen: LZTR1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human LZTR1. The immunogen is located within amino acids 130 - 180 of LZTR1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LZTR1 antibody can be used for detection of LZTR1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LZTR1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LZTR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LZTR1

Target: LZTR1 (Leucine-Zipper-Like Transcription Regulator 1 (LZTR1))

Andere Bezeichnung: LZTR1 (LZTR1 Produkte)

Hintergrund: LZTR1 Antibody: LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.

Gen-ID: 8216

UniProt: Q8N653