WDR35 Antikörper (N-Term)
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- Target Alle WDR35 Antikörper anzeigen
- WDR35 (WD Repeat Domain 35 (WDR35))
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Bindungsspezifität
- AA 60-110, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WDR35 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- WDR35 antibody is human specific.
- Aufreinigung
- WDR35 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- WDR35 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human WDR35. The immunogen is located within amino acids 60 - 110 of WDR35.
- Isotyp
- IgG
- Top Product
- Discover our top product WDR35 Primärantikörper
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- Applikationshinweise
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WDR35 antibody can be used for detection of WDR35 by immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- WDR35 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- WDR35 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- WDR35 (WD Repeat Domain 35 (WDR35))
- Andere Bezeichnung
- WDR35 (WDR35 Produkte)
- Synonyme
- 4930459M12Rik antikoerper, 4931430C06 antikoerper, mKIAA1336 antikoerper, RGD1564116 antikoerper, Wdr35 antikoerper, CED2 antikoerper, IFT121 antikoerper, im:7159945 antikoerper, si:ch211-206k20.4 antikoerper, WD repeat domain 35 antikoerper, Wdr35 antikoerper, WDR35 antikoerper, wdr35 antikoerper
- Hintergrund
- WDR35 Antibody: WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.
- Gen-ID
- 57539
- NCBI Accession
- NP_001006658
- UniProt
- Q9P2L0
- Pathways
- Hedgehog Signalweg
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