KPNA5 antibody is human specific. KPNA5 antibody is predicted to not cross-react with other Importin alpha family members.
Aufreinigung
KPNA5 Antibody is affinity chromatography purified via peptide column.
Immunogen
KPNA5 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human KPNA5. The immunogen is located within amino acids 30 - 80 of KPNA5.
KPNA5
Reaktivität: Human
WB, IF, ICC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
KPNA5 antibody can be used for detection of KPNA5 by immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
KPNA5 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
KPNA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
KPNA5 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA5 belongs to a subfamily within the KPNA family that also includes KPNA4 and 6 and is thought to be involved in NLS-dependent protein import into the nucleus.