TRIP6 Antikörper (AA 190-240)

Produktnummer ABIN6991423

Produktdetails anti-TRIP6 Antikörper

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Bindungsspezifität: AA 190-240

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Aufreinigung: TRIP6 Antibody is affinity chromatography purified via peptide column.

Immunogen: TRIP6 antibody was raised against a 15 amino acid synthetic peptide near the center of human TRIP6. The immunogen is located within amino acids 190 - 240 of TRIP6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TRIP6 antibody can be used for detection of TRIP6 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TRIP6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TRIP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TRIP6

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Andere Bezeichnung: TRIP6 (TRIP6 Produkte)

Synonyme: TRIP6 antikoerper, OIP-1 antikoerper, OIP1 antikoerper, TRIP-6 antikoerper, TRIP6i2 antikoerper, ZRP-1 antikoerper, thyroid hormone receptor interactor 6 antikoerper, TRIP6 antikoerper, Trip6 antikoerper

Hintergrund: TRIP6 Antibody: TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-κ,B activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.

Gen-ID: 7205

NCBI Accession: NP_003293

UniProt: Q15654

Pathways: Cell-Cell Junction Organization