PEAR1 Antikörper (C-Term)

Produktnummer ABIN6991445

Produktdetails anti-PEAR1 Antikörper

Target: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEAR1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: PEAR1 Antibody is affinity chromatography purified via peptide column.

Immunogen: PEAR1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PEAR1. The immunogen is located within the last 50 amino acids of PEAR1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PEAR1 antibody can be used for detection of PEAR1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PEAR1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PEAR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PEAR1

Target: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Andere Bezeichnung: PEAR1 (PEAR1 Produkte)

Synonyme: MEGF12 antikoerper, JEDI antikoerper, 3110045G13Rik antikoerper, Jedi-1 antikoerper, Megf12 antikoerper, RGD1305653 antikoerper, platelet endothelial aggregation receptor 1 antikoerper, PEAR1 antikoerper, pear1 antikoerper, Pear1 antikoerper

Hintergrund: PEAR1 Antibody: Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated, the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.

Gen-ID: 375033

NCBI Accession: NP_001073940

UniProt: Q5VY43