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N4BP1 Antikörper (N-Term)

N4BP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991485
  • Target Alle N4BP1 Antikörper anzeigen
    N4BP1 (NEDD4 Binding Protein 1 (N4BP1))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 14
    • 1
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser N4BP1 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    At least three isoforms of N4BP1 are known to exist, this antibody will only detect the longest isoform.
    Aufreinigung
    N4BP1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    N4BP1 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human N4BP1. The immunogen is located within the first 50 amino acids of N4BP1.
    Isotyp
    IgG
    Top Product
    Discover our top product N4BP1 Primärantikörper
  • Applikationshinweise
    N4BP1 antibody can be used for detection of N4BP1 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    N4BP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    N4BP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    N4BP1 (NEDD4 Binding Protein 1 (N4BP1))
    Andere Bezeichnung
    N4BP1 (N4BP1 Produkte)
    Synonyme
    AI481586 antikoerper, C81621 antikoerper, RGD1305179 antikoerper, wu:fi03b05 antikoerper, zgc:66437 antikoerper, NEDD4 binding protein 1 antikoerper, Nedd4 binding protein 1 antikoerper, nedd4 binding protein 1 antikoerper, nedd4 binding protein 1 L homeolog antikoerper, N4BP1 antikoerper, N4bp1 antikoerper, n4bp1 antikoerper, n4bp1.L antikoerper
    Hintergrund
    N4BP1 Antibody: Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
    Gen-ID
    9683
    NCBI Accession
    NP_694574
    UniProt
    O75113
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